Master of Science
Walter Henne, Jr., Ph.D.
Joong-Won Shin, Ph.D.
Kulugammana Ranmohotti, Ph.D.
Folic acid has been frequently exploited for target therapies geared toward overexpressed folate receptors on malignant cells. The folic acid/folate-receptor high affinity interaction can be used to not only target but image cancer cells. Folate-linked nanoparticles represent a potential new drug carrier for tumor cell-selective therapeutics. Folate targeting, nanoparticles in therapeutics, and cancer cell imaging will be outlined in this literature report.
Carr, Mekeda, "Folate Targeted Agents for Diagnostic and Therapeutic Uses" (2014). All Capstone Projects. 88.