Publication Date

Fall 2014

Document Type

Project Summary

Degree Name

Master of Science


Analytical Chemistry

First Advisor

Walter Henne, Jr., Ph.D.

Second Advisor

Joong-Won Shin, Ph.D.

Third Advisor

Kulugammana Ranmohotti, Ph.D.


Folic acid has been frequently exploited for target therapies geared toward overexpressed folate receptors on malignant cells. The folic acid/folate-receptor high affinity interaction can be used to not only target but image cancer cells. Folate-linked nanoparticles represent a potential new drug carrier for tumor cell-selective therapeutics. Folate targeting, nanoparticles in therapeutics, and cancer cell imaging will be outlined in this literature report.

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