Novel Approaches Towards the Synthesis of Benz-fused Five- and Six-Membered Azoles

Type of Presentation

Panel

Location

D34011

Start Date

4-16-2025 3:00 PM

End Date

4-16-2025 3:30 PM

Description of Program

New methodologies for the synthesis of benz-fused 5-membered heterocycles from thiocarbonyl precursors are reported. Oxidative cyclization of various 2-substituted benzene thiocarbonyls was effected using basic ferricyanide, AIBN, iodine and thermal conditions to produce benzothiazoles, benzoxazoles, benzimidazoles and benzothiophenes. This work was extended to benzofurans, benzothiophens, and potentially, benz-fused six-membered azoles analogs.

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Apr 16th, 3:00 PM Apr 16th, 3:30 PM

Novel Approaches Towards the Synthesis of Benz-fused Five- and Six-Membered Azoles

D34011