Publication Date

Summer 2016

Document Type

Project Summary

Degree Name

Master of Science

Department

Analytical Chemistry

First Advisor

Walter Henne, Jr., Ph.D.

Second Advisor

K. G. Sanjaya Ranmohotti, Ph.D.

Third Advisor

Stephen Kent, M.B.A.

Abstract

A priority of chromatographers is to eliminate extraneous and errant noise that can interfere with any experiment. The goal is to focus on what is being analyzed, and in the case of detectors, modifying the instrument being utilized is the method of choice. One way to do that in ion chromatography (IC) is through the use of a suppressor.

Though not all instruments utilized in IC are equipped with suppressors, it is ideal to help reduce the ions already known to be present in the eluent. The premise of this study is simple in nature, but important in its application. It is to ensure the efficacy of a new suppressor prior to its use in everyday workflow. Without the suppressor in use, the instrument would provide data convoluted with extra noise and peaks, which would make analysis of samples unnecessarily tedious. With a suppressor installed in the ion chromatography system (ICS), the baseline can be more stable, the signal-to-noise ratio would be at its optimal level, and sensitivity of the ICS would be enhanced as well.

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