Publication Date

Spring 2014

Document Type

Project Summary

Degree Name

Master of Science


Analytical Chemistry

First Advisor

Karen D'Arcy, Ph.D.

Second Advisor

Stephen Kent, M.B.A.

Third Advisor

Joong-Won Shin, Ph.D.


Pharmaceuticals and Personal Care Products (PPCP) in surface waters is a worldwide concern. Effluent from waste water treatment plants have tested positive for PPCP. Method development for a liquid chromatographic method was derived using columns with fused core technology. Analysis of spiked samples as direct injection and after solid phase extraction indicated detection of acetaminophen, caffeine, bisphenol-A and triclosan. Confirmation of acetaminophen, caffeine, bisphenol-A and triclosan was achieved using Agilent 1100 HPLC with Agilent MST Trap XCT. Solid phase extraction using Oasis HLB indicated reproducibility at 0.05ppm.