Psychological Factors Influencing Wound Healing Outcomes and Quality of Life in Adults with Chronic Wounds: A Scoping Review

Publication Date

Spring 2026

Document Type

Capstone Project

Degree Name

Doctor of Physical Therapy

Department

Physical Therapy

First Advisor

Amy Bala

Second Advisor

Laura Lenhart

Third Advisor

Nicole Stotts

Abstract

Chronic wounds are a significant healthcare burden, often associated with long healing times, reduced QoL, and limited functional mobility. Affected individuals often experience pain and limited ability to perform activities of daily living (ADLs), leading to social isolation and decreased participation in meaningful roles. While non-traditional, psychological factors are becoming increasingly recognized for their influence on wound healing outcomes and well-being. The purpose of our scoping review was to answer the following question: What are the psychological factors that influence wound healing outcomes and quality of life in adults with chronic wounds? Inclusion criteria: peer-reviewed articles within the past 10 years (2015-2025), fell text, written in English, and participants with chronic wounds. Exclusion criteria: Articles older than 10 years, pressure injuries and burns, acute wounds, systematic reviews and meta-analyses. The databases accessed were PubMed, EBSCO, Web of Science, and a variety of individual Wound Journals. This scoping review was conducted by six members following the PRISMA-ScR methodology protocol. After screening, 39 articles were reviewed by the members to determine eligibility through unanimous agreement. Nine studies met the inclusion criteria, encompassing varied designs and conducted across multiple countries. Common outcome measures included DLQI and Wound-QoL, alongside general functional and mental health tools (EQ-5D, Barthel Index, HADS, WHO-5, GHQ-12). Three key themes emerged; those being wound location, anxiety/depression, and social isolation. This clinical line of inquiry is important as chronic wounds are prevalent in the population of people who seek care. Gaps identified within the research include limited current research on psychological factors impacting wound healing as well as location of wounds discussed in the referenced articles.

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