Folate Targeted Agents for Diagnostic and Therapeutic Uses

Author

Mekeda Carr, Governors State University

Publication Date

Fall 2014

Document Type

Project Summary

Degree Name

Master of Science

Department

Analytical Chemistry

First Advisor

Walter Henne, Jr., Ph.D.

Second Advisor

Joong-Won Shin, Ph.D.

Third Advisor

Kulugammana Ranmohotti, Ph.D.

Abstract

Folic acid has been frequently exploited for target therapies geared toward overexpressed folate receptors on malignant cells. The folic acid/folate-receptor high affinity interaction can be used to not only target but image cancer cells. Folate-linked nanoparticles represent a potential new drug carrier for tumor cell-selective therapeutics. Folate targeting, nanoparticles in therapeutics, and cancer cell imaging will be outlined in this literature report.

Recommended Citation

Carr, Mekeda, "Folate Targeted Agents for Diagnostic and Therapeutic Uses" (2014). All Capstone Projects. 88.
https://opus.govst.edu/capstones/88